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The Hahaguffawchuckleamalus is a purple brain lobe that appears only in Captain Underpants: The First Epic Movie. The size of the lobe determines a person's capacity for laughter. People with large Hahaguffawchuckleamaluses have a huge sense of humor, while those with small or no Hahaguffawchuckleamaluses are humorless.

Professor Poopypants's goal in the movie is to shrink or even remove the Hahaguffawchuckleamalus, ridding the world of laughter in the process. Melvin Sneedly does not have the Hahaguffawchuckleamalus, making his brain power essential to Poopypants' evil plan.


  • Despite lacking a Hahaguffawchuckleamalus in the movie, in The Epic Tales of Captain Underpants, Melvin is shown laughing multiple times throughout the series.
  • George and Harold have the biggest Hahaguffawchuckleamaluses out of all the children in the movie.