Mrs. DePoint is part of a trio of lunch ladies. Her name is a pun to the sentence "misses the point." George and Harold forge a cupcake recipe, claiming it to be for Mr Krupp's birthday. The lunch ladies then use a batch 100 times the intended size and the school is flooded with slime. The lunch ladies then tell Mr Krupp that they are quitting and after they walk out on Mr Krupp, Zorx, Klax and Jennifer take over.
Her name is literally a pun of the phrase “misses the point”.